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The cellular defense against reactive oxygen species relies on antioxidant enzymes and small molecules. L-ergothioneine, a powerful antioxidant obtained from the diet, accumulates in cells exposed to high oxidative stress. Its protective role depends on the L-ergothioneine-specific receptor/transporter OCTN1, as it cannot permeate the plasma membrane.

The cellular defense against reactive oxygen species relies on antioxidant enzymes and small molecules. L-ergothioneine, a powerful antioxidant obtained from the diet, accumulates in cells exposed to high oxidative stress. Its protective role depends on the L-ergothioneine-specific receptor/transporter OCTN1, as it cannot permeate the plasma membrane.

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells, which plays a vital role in various metabolic processes. NAD+ can potentially improve skin health by boosting cellular energy and promoting repair, leading to reduced wrinkles and enhanced skin texture.

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An unsung hero for a healthy skin barrier. Phytospingosine strengthens the outermost layer of the skin and is very well tolerated and has a wide range of applications. The outermost layer of our skin is responsible for not only keeping moisture from getting out, but also irritants and toxins from getting in. Thus when the barrier is compromised or weakened, unwanted factors can get in, resulting in all kinds of issues from redness to rashes. As well for acne vulgaris different pathogenic factors contribute to the inflammation process. Studies confirmed the strong anti microbial and anti inflammatory activity and the efficassy of phytospingosine adressing acne vulgaris. It strengthens the skin barrier so moisture is kept in and irritants are not let in. It triggers the production of natural moisturizing factors and delivers anti-inflammatory and antibacterial effects.

Phytospingosine is COSMOS registered and is used at levels from 0.1 to 1%

Salicyloyl Phytosphingosine is an innovative ceramide derivative with remarkable anti-aging and skin-restoring properties. Formed by the reaction of salicylic acid and phytosphingosine - a natural component of human skin - it combines the conditioning and anti-inflammatory benefits of phytosphingosine with the enhanced absorption properties of salicylic acid.

This multifunctional ingredient stimulates the skin’s natural production of collagen and extracellular matrix proteins, helping to improve firmness and elasticity. Clinical studies have shown that topical application reduces wrinkle depth, smooths skin texture, and alleviates visible signs of photoaging. Additionally, it combats oxidative stress, promotes hydration, and supports a more even skin tone by inhibiting excessive pigmentation.

Beyond its anti-wrinkle and firming effects, Salicyloyl Phytosphingosine strengthens the dermal-epidermal junction, refines pore appearance, and soothes inflammation thanks to its anti-inflammatory and antibacterial properties. As a result, it helps restore a youthful, radiant complexion while supporting overall skin health.

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Typical applications:

- include photoaged skin treatments

- after-sun care

- soothing formulations

- skin renewal and repair products

- advanced anti-aging skincare